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NFL Picks Against the Spread Week 5

With some tremendous surprises and upsets already this season, the 2022 NFL season is now in full swing. With our in-house specialists and computer models, we’ve discovered the greatest ATS picks for week 5.

Thursday Night Football

Indianapolis Colts @ Denver Broncos

The Colts’ excellent rush defense will put this game into Wilson’s hands, and I don’t trust him to deliver a decisive win. Matt Ryan has slowly looked like the veteran QB he is and the Broncos are dealing with turnovers right now. I love the upset play here as the Colts steal one from Denver.

Key Betting Trend: Colts are 12-3 ATS in their last 15 games in Week 5.

  • ATS: Colts +3.5 / ML

Sunday Football

New York Giants @ Green Bay Packers

  • ATS: Packers -8

Detroit Lions @ New England Patriots

  • ATS: Lions +3

Los Angeles Chargers @ Cleveland Browns

  • ATS: Browns +3

Tennessee Titans @ Washington Commanders

  • ATS: Commanders +2.5

Pittsburgh Steelers @ Buffalo Bills

  • ATS: Bills -14

Atlanta Falcons @ Tampa Bay Buccaneers

  • ATS: Buccaneers -8

Houston Texans @ Jacksonville Jaguars

  • ATS: Jaguars -7

Miami Dolphins @ New York Jets

  • ATS: Jets +3

Seattle Seahawks @ New Orleans Saints

  • ATS: Saints -5

Chicago Bears @ Minnesota Vikings

  • ATS: Vikings -7

San Francisco 49ers @ Carolina Panthers

  • ATS: 49ers -6.5

Philadelphia Eagles @ Arizona Cardinals

  • ATS: Eagles -5.5

Dallas Cowboys @ Los Angeles Rams

The Los Angeles Rams are struggling trying to protect Matthew Stafford right now as they allowed seven sacks against the 49ers. The Cowboys defense is no different. Rams struggle once more.

Key Betting Trend: Cowboys are 16-5 ATS in their last 21 vs. NFC.

  • ATS: Cowboys +4

Sunday Night Football

Cincinnati Bengals @ Baltimore Ravens

The Cincinnati Bengals are off a great win over the Miami Dolphins but was it the best win ever? They struggled to put the game away and now take on rough Ravens defense that will go after Burrow.

Key Betting Trend: Ravens are 8-3 ATS in their last 11 games following a straight up loss.

  • ATS: Ravens -3

Monday Night Football

Las Vegas Raiders @ Kansas City Chiefs

The Las Vegas Raiders were gifted their first win of the season last week against the Denver Broncos only because Melvin Gordon could not hang onto the ball. Well Kansas City will not have that issue here.

Key Betting Trend: Chiefs are 9-3 ATS in their last 12 games on grass.

  • ATS: Chiefs -7
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